We do not endorse non-Cleveland Clinic products or services. Factor V Deficiency Vs. There is no specific "diet" for people with factor V Leiden, but there are foods that can help keep your blood and body healthy, which may reduce your risk of developing a blood clot. Check with your provider. Cranberry juice and other cranberry products can alter the effects of anticoagulants. Healthy fats: Eat healthy fats each day such as olive oil, nuts, seeds and avocado. Factor V Leiden may lead to deep vein thrombosis or a pulmonary embolism, which are serious medical emergencies. Lockwood CJ, et al. Get useful, helpful and relevant health + wellness information. >_IJ9D/\KwrokzHI7lw7B+Vefcr2L`/R6:s#oI`HlG&W|Az_hSafLG*!~?k{Xi|2`7Q\GcLb9'I |./(-k$Bw&uooR`";j$6GKE:t.0V* II'LX2Q074H4bXh. 3&&}o#Rf,M%>i_+23#_~Ub7{1e9O6I@iQ>,L8?@e"XFExot!^>P(@|` 9 ;90{7,N9|Xf@68-VQBaqL8E-u^5iT Id9l'U"ec BW">)W#idirh#Z>w(!($|1Pa_-780 E71>CCJ8VF}mAGLS!qqEb3 1AEd 'DG/syWtbhF#'. When you are ready, talk with your health care provider for advice and help to lose weight. Some issues that can be discussed with your doctor include: Other than the increased risk of developing DVT or PE, factor V Leiden may increase the risk of miscarriage or other pregnancy complications, such as preeclampsia and eclampsia, placental abruption (when the placenta separates too early from the wall of your uterus), and having a fetus that grows slower than is usual. People with Factor V Leiden make an altered factor V protein as a result of a mutated gene. Wear compression stockings if your provider prescribes them for you. a V@ C= Fruits and vegetables: Get at least five servings of fruits and veggies throughout the day, and incorporate all different kinds. 2. Is an uncertain result possible, and what would that mean? Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. ", cdc.gov: "How much physical activity do adults need?". Late in my pregnancy I started having horrible swelling in my legs. Accessed June 4, 2018. Camomile in large quantities, a herbal treatment that is used to treat anxiety, catarrh and gastric problems, has also been implicated in a case of severe bleeding in a 70-year-old woman. As such, daily intake or extra supplementation with vitamin K is typically unnecessary to keep body stores at healthy levels. When you need health care or go to the hospital, tell your healthcare team that you have Factor V Leiden, so that they can plan the care you need. Is this an emergency? Youre might be wondering, Will this happen to me? RTs endorsements. Zoppi, Lois. If you have the disorder, you may never develop a blood clot. People with this condition have a factor V Leiden mutation, meaning theres a change in their coagulation factor V (F5) gene. As a result, too much blood clotting can happen. Vitamin K is necessary for making the proteins that aid in blood clotting, according to the Harvard T.H. Vitamin K is a necessary element in the blood clotting process. The two most common hematological diseases the impairment of Factor V causes are Factor V deficiency or Owren's disease, and Factor V Leiden. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. At this time, we cant treat or change our genes. Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. For those who are watching their cholesterol, there have been some studies that show low GI diets are helpful at lowering cholesterol levels. of signs you need emergency medical attention or call 911. The Factor V Leiden protein is harder to turn off than the normal Factor V protein. Do I need to limit my activity in any way? Factor V Leiden This results from a genetic change that increases the risk of blood clots, especially in deep veins. Factor V and other proteins work together to help your blood clot when necessary. You won't go hungry on The 5-Factor Diet. But the plan would have to be modified to make it appropriate if you have these or other conditions. If youcannot reach your doctor, go to the nearest hospital emergency room. Factor V Leiden and prothrombin gene mutations cause about 50% of inherited coagulopathies. AskMayoExpert. When you are injured, your body stops bleeding by changing liquid blood into a plug (clot) that blocks the leaks in damaged blood vessels. However, some people with this disorder develop DVT or PE. They were hot, red, and huge. Factor V Leiden. These precautions might include: Some precautions to help reduce your risk of blood clots include: If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding: Your doctor may refer you to a specialist in genetic disorders (geneticist) or a specialist in blood disorders (hematologist) for testing to determine whether the cause of your blood clots is genetic and, specifically, whether you have factor V Leiden. Some people do not have the normal Factor V protein. 3. Just by eliminating junk food, simple carbs, and high-calorie drinks, as in the 5-Factor Diet, most people are likely to see a dip on the scale. If you have this disorder, you may experience: Factor V Leiden doesnt raise your risk of heart attacks, strokes or blood clots in the arteries of your legs. Youll spend roughly the same amount on groceries if you keep the bulk of your protein purchases to eggs, lean meats and poultry, and fat-free dairy, as opposed to seafood. Why Am I Still Anemic After Taking Iron Supplements? Factor V Leiden is an inherited blood clotting disorder that raises your risk of deep vein thrombosis or a pulmonary embolism. Please note that medical information found This can be a life-threatening situation. Usually, once the clot is formed, factor V is "turned off," but not in those with factor V Leiden. The clot remains in place while other enzymes repair the damaged blood vessel. As a result, clotting goes on longer than usual. How long do I need to take the anticoagulant? Diets ideal for this include the Mediterranean diet and the DASH diet. ABSTRACT: Factor V Leiden thrombophilia is a genetic disorder that may increase a patient's risk of developing a venous thromboembolism (VTE). National Heart, Lung, and Blood Institute. You inherited one Factor V Leiden gene from your mother and one from your father. Our mission of spreading lifesaving #bloodclot awareness is possible thanks to the generous support of our partners. Most people who inherit it never develop abnormal blood clots, and may never even know they have the disorder. Factor V Leiden is also known under its other name Factor V Leiden Thrombophilia. Factor V Leiden is the most common one. If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding: Avoid playing contact sports or engaging in other activities that could result in physical injury. What are the chances of passing down the genetic mutation to my children? You inherit this condition from one of your biological parents. Your brothers and sisters may have inherited the mutated gene for Factor V Leiden, just like you did. Yes, you can pass on the gene for this disorder to your children. If I have children, do they need to be tested? NBCA provides the information and materials on this site for general information purposes only. You may substitute gluten-free alternatives as long as they are low-sugar. What websites do you recommend? A mutation in your F5 gene causes this disorder, which follows an autosomal dominant inheritance pattern. Factor V Leiden is an inherited disorder. It does not increase the risk of myocardial infarction (heart attacks) or arterial strokes. Factor V Leiden resists the effects of Activated Protein C, so it takes longer to turn off Factor V Leiden. As they come, write them down. If you cant walk around, flex your ankles and point your toes up and down. High-Protein Diets -- Do They Really Work? But some factors raise your risk of developing clots. 0000003221 00000 n "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. If you have the heterozygous type, there is a 50% chance that your child will inherit a Factor V Leiden gene from you. Healthy fat (from fish such as salmon, tuna, mackerel, sardines, rainbow trout, or peanut oil, olive oil, canola oil, sunflower oil, Sugar-free drinks (water, sugar-free soda, coffee, tea, or an unsweetened energy drink). With Factor V Leiden the risk of a blood clot increases with age 0 100 200 300 400 500 600 700 800 900 1000 Risk per 100,000 people Childhood 20's 40's 80's Having 1 Factor V Leiden gene (heterozygous type) slightly increases the chance of developing a blood clot. Though exercise is an important part of the 5-Factor Diet, the recommended amount falls a bit short of the 150 minutes a week of aerobic activity coupled with strength training that most experts recommend. In general, you should avoid: You can help lower your risk of blood clots with lifestyle changes, including: Visit your provider for a yearly checkup. Diseasemaps 2023, FACTORV LEIDEN AND LIVEDOID VASCULOPATHY SURVIVOR. You may never get a dangerous clot, but its helpful to know the warning signs in case you do. 76 0 obj<> endobj Added sugars in excess of 24 grams per day for people assigned female at birth and 32 grams per day for people assigned male at birth, per the American Heart Association. This site complies with the HONcode standard for trustworthy health information: verify here. Cranberry products are not significant unless taken in high amounts, as for urinary infections. A blood test (called a screening test) can show if you have Activated Protein C resistance. Philadelphia, PA 19182-5687. Still, there is research that suggests that a diet of low GI foods is more likely to cause weight loss, at least in the short term. How frequently do I need to have checkups. Your doctor can tell you how much fluid is right for your age, health and activity level. with these terms and conditions. 0000000016 00000 n If you are already taking an anticoagulant, make sure you keep regular appointments with your provider. Follow Canadas Physical Activity Guide. 2. If you have symptoms of a pulmonary embolism, you should go to the closest emergency room. If you do, another blood test that examines your genes (called DNA) will be done to find out if Factor V Leiden is the cause of the resistance and what type of Factor V Leiden you have. Some research suggests that women with the Factor V Leiden gene who have had pregnancy losses may have a greater risk of miscarriages. What are my risks? This means that for children with factor V Leiden, one out of 5,000-10,000 will get a blood clot. The clot remains in place while other enzymes repair the damaged blood vessel. A single copy of these materials may be reprinted for noncommercial personal use only. Having Factor V Leiden does not appear to increase the chances of developing a heart attack or stroke. Its important to go to all of your appointments and talk to your provider about any questions or concerns you have. The length of treatment may vary depending on your situation. About 1 of every 250 Black people in America has the prothrombin gene mutation. 3. Depending on the severity of symptoms, other treatments may be necessary as well. Factor V Leiden makes you more likely to develop: Its important to know that people with factor V Leiden wont necessarily develop DVT or PE. The different gene that makes the Factor V Leiden protein is inherited from one or both parents. We do not endorse non-Cleveland Clinic products or services. Foods containing trans fat, including hydrogenated oils and highly processed shelf-stable food (think: packaged snacks and baked goods). Most people with this disorder never develop a blood clot. This site complies with the HONcode standard for trustworthy health information: verify here. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Owned and operated by AZoNetwork, 2000-2023. Factor V Leiden thrombophilia. Factor V is a helper in the enzyme reactions that form the fibrin in the clot.